Pharmaquinone®: The Purest Vitamin K2 in the World

1. Introduction to Vitamin K2

Vitamin K2 is a vital component in health and nutrition, known for its profound impact on various physiological processes. Unlike Vitamin K1, which mainly contributes to blood clotting, Vitamin K2 plays a crucial role in calcium metabolism, bone health, and cardiovascular function. This distinction has made Vitamin K2 a sought-after ingredient in nutritional products, dietary supplements, and functional foods.

The importance of Vitamin K2 extends beyond traditional applications to areas like sports nutrition, brain health, and even topical use. As the scientific community continues to uncover its benefits, the demand for high-quality, pure Vitamin K2 is growing rapidly. However, the quality of Vitamin K2 products on the market varies significantly, emphasizing the need for stringent production and analytical standards to meet the expectations of the industry and consumers.

2. Pharmaquinone®: The Purest Vitamin K2 in the World

Vitamin K2, commonly recognized as Vitamin K2 MK-7, exists in two main isomeric forms: cis and trans. Among these, only the trans isomer offers high bioactivity and the best efficacy. Producing Vitamin K2 MK-7 with 100% trans isomer content is a significant challenge, leading to inconsistent quality in many products on the market.

According to the European Union (EU) regulations, Vitamin K2 MK-7 products must adhere to strict standards:

• The cis isomer content must not exceed 6%.
• Unidentified impurities must remain below 2%.

Complying with these rigorous EU regulations, Pharmaquinone® is a Vitamin K2 (MK-7) with absolute all-trans purity. VitaSynth's advanced production processes ensure that the cis isomer content (less effective) remains extremely low. Pharmaquinone® stands out as one of the leading products, guaranteeing the highest standards of trans isomer purity and content, providing absolute trust for consumers and manufacturing partners.

2.1 Pharmaquinone®: Superior Quality Compared to USP Reference Standards

Through the US Pharmacopeia® (USP) method—an industry-standard approach to evaluating Vitamin K2 MK-7 quality—and the more stringent Ultra Performance Liquid Chromatography (UPLC) method, Pharmaquinone® demonstrates its commitment to exceeding industry standards. While USP provides an overall purity assessment, UPLC identifies additional peaks, revealing impurities often overlooked by conventional techniques.

The analytical results and comparison with USP standards are as follows:

• Absolute Purity: Testing three batches of Pharmaquinone® raw materials using both methods (USP and UPLC) yielded:
• USP Method: Pharmaquinone achieved 100% all-trans, with only one peak on the chromatogram.
• UPLC Method: Minimum purity reached 99.98% all-trans.

Pharmaquinone®'s standard batches not only meet but regularly exceed USP's stringent requirements for purity and content. The isomer purity of our active ingredient consistently achieves 100% (no cis isomer detected by the USP method), defining the pharmaceutical-grade quality of the product we supply.

2.2 Pharmaquinone®: Second-Generation Vitamin K2 MK-7 Produced with Proprietary Technology

To deliver such exceptional purity and stability, VitaSynth (headquartered in Poland) has successfully developed second-generation proprietary technology for producing 100% all-trans Vitamin K2 MK-7 over the past 14 years.

Second-generation Vitamin K2 MK-7 synthesis technology represents significant improvements over the first generation, including:

• Higher Efficiency: Reducing steps or costs in the synthesis process.
• Improved Purity: Achieving a higher ratio of bioactive all-trans isomer.
• Enhanced Stability: Improving shelf life and product performance.

As a result, Pharmaquinone® offers competitive pricing while maintaining superior quality standards.

3. Applications of Pharmaquinone®

The innovations of Pharmaquinone® and VitaSynth represent a significant leap forward in the Vitamin K2 market. From enhancing bone and joint health, supporting height growth and cardiovascular function, to boosting brain health,... the applications of Vitamin K2 are incredibly diverse.

References: VitaSynth