What is M-Gard®? And How Does it Support Immunity?

In the context of the flu spreading in many places, and especially after the COVID-19 pandemic, many consumers have developed a more comprehensive view of immune health. According to FMCG Gurus’ Global Immunity Survey, April 2024, 30% of global consumers consider immune health one of their primary physical health concerns, and 39% use supplements primarily to boost immunity. Among these, Asian consumers are most likely to use immune-boosting supplements regularly.

M-Gard® is considered an effective solution, regarded as the "master" of the immune system, helping the body defend against harmful agents such as bacteria, viruses, and fungi.

What is M-Gard®?

M-Gard® is a purified bioactive beta-1,3/1,6-glucan, a naturally occurring complex polysaccharide found in the cell walls of baker’s yeast. 

M-Gard® is an immunomodulator that enhances your body’s vital defense mechanisms against bacteria, viruses, fungus, etc. Studies have shown that M-Gard® exerts immunomodulatory effects in vitro and in vivo in experimental animal and human models. M-Gard® represents an excellent immune-enhancing compound for human use.

Produced in the world’s northernmost beta-glucan facility, M-Gard® adheres to the highest quality standards, including GMP, Halal, Kosher, and GRAS certifications. Its natural derivation, non-GMO status, and allergen-free profile make it a trusted choice for dietary supplements and functional foods.

How M-Gard® enhances your immune system

The immune system is your body’s first line of defense against infections, environmental toxins, and cellular damage. However, factors like stress, poor diet, and pollution can weaken immune function, leaving you vulnerable to illness. M-Gard® addresses these challenges by interacting with specific receptors on immune cells, such as monocytes, macrophages, dendritic cells, and natural killer cells

Step 1: The unique molecular structure of the bioactive M-Gard® lets it bind to specific receptors on immune cells. This interaction is known to occur through different cell surface receptors — most notably, the Dectin-1 receptor.

Step 2: Binding of M-Gard® to a receptor triggers cellular signaling cascades, which modulates the immune cell that is part of the innate immune system.

Step 3: The underlying mechanism of M-Gard® is represented by modulation of the innate immune system, leading to enhanced immune responses upon infection (enhanced secretion of cytokines).

What makes M-Gard® unique?

The common feature of glucans that can activate the immune system is a chain of glucose molecules linked together by beta-1,3 bonds. However, to achieve maximum biological activity, "branches" of glucose molecules must be attached (via beta-1,6 bonds) to the beta-1,3-glucan chain. M-Gard®, with a minimum 80% yeast beta-glucan derived from yeast and a corresponding beta-1,3/1,6-glucan structure, demonstrates a very strong immune-regulating capability.

When compared to other glucans: 

• Beta-glucans derived from barley, oats, and other cereals have a completely different chemical structure from M-Gard®. They contain a significant proportion of beta-1,4 bonds, making them less effective in immune regulation.
• On the other hand, beta-glucans derived from brewer's yeast are typically by-products of the beer fermentation process and are anaerobic yeasts. M-Gard®, however, is derived from baker's yeast (aerobic yeast), which makes M-Gard® more effective in boosting the immune system.

The exclusive refinement process ensures that M-Gard® has an optimized structure, making it far more potent than other beta-glucan products.

M-Gard®, Scientifically Proven Effectiveness

The effects of M-Gard® are supported by research and scientific evidence obtained across various fields (animal health, pharmaceuticals, medical devices) and among various groups (Children, Elderly, people with a weak immune system, stressed people, Athletes), with many studies published in peer-reviewed scientific journals:

• Improves clearance of virus (Hepatitis B virus)
• Enhances the expression of cytokines
• Increases the protection against the influenza virus
• Protects against infection diseases
• Potentiates the antibody response

Applications of M-Gard® in the Market Today

In an era where preventive immune health is crucial, M-Gard® stands out as a targeted immune booster, scientifically validated. Its unique molecular structure, proven effectiveness, and commitment to quality make it an invaluable ingredient for businesses in the dietary supplement and nutrition industry.

Thanks to its high thermal stability and ability to remain effective across different pH conditions, M-Gard® can easily be added to gummies, syrups, capsules, tablets, powders, and immune-boosting foods and beverages while maintaining efficacy. Additionally, its 5-year shelf life ensures long-term quality, meeting the demands of manufacturers.

Source: www.bio-lallemand.com